Moderna–Merck Cancer Vaccine Shows Durable Benefit At 5 Years In High-Risk Melanoma

Moderna Inc. (NASDAQ:MRNA) and Merck & Co. Inc. (NYSE:MRK) on Tuesday shared median five-year follow-up data from the Phase 2b KEYNOTE-942/mRNA-4157-P201 study of mRNA-based individualized neoantigen therapy for a serious type of skin cancer.

The trial evaluated intismeran autogene (mRNA-4157 or V940) in combination with Merck’s Keytruda (pembrolizumab) for high-risk melanoma (stage III/IV) following complete resection (removed surgically).

In this pre-planned analysis, adjuvant treatment with intismeran autogene plus Keytruda demonstrates sustained and clinically meaningful improvement in the study’s primary endpoint, recurrence-free survival (RFS), reducing the risk of recurrence or death by 49% compared to Keytruda alone.

Moderna and Merck plan to present further data from follow-up analyses of primary and secondary endpoints at an ...

Back to News

Ready to start trading futures?

Get Started More News

DayTraders.com provides educational resources and access to simulated trading environments. We do not facilitate the deposit or trading of actual funds. Participation in the futures markets involves significant risk, and it is essential that individuals fully understand these risks before engaging in trading activities elsewhere. Below are key points regarding the risks.

Educational Purpose Only: All content and resources provided by DayTraders.com, including simulated trading environments, are for educational purposes. We do not offer real-money trading accounts, and no actual funds are deposited with or traded through our platform.

High Risk of Loss in Actual Trading: While DayTraders.com offers simulated trading environments, actual futures and derivatives trading conducted through a brokerage firm involves significant risk. In real trading, substantial financial loss can occur. Participants should only trade with capital they can afford to lose.

Leverage and Margin Risks: In actual trading environments, using leverage or trading on margin can significantly magnify both gains and losses. Traders should be aware of these risks and fully understand the implications of margin before engaging in real-money trading outside DayTraders.com.

Market Volatility: The financial markets are subject to rapid and unpredictable changes. While the simulated environment on DayTraders.com may help users practice strategies, real market volatility can lead to substantial losses. This volatility can be influenced by economic data, geopolitical events, and other factors beyond anyone's control.

No Guarantees of Profit: DayTraders.com does not guarantee profit or success in actual trading. Past performance in our simulated environment, whether favorable or not, is not indicative of future results when trading real funds in the marketplace.

Technological and Operational Risks: While DayTraders.com provides a stable simulated environment for educational purposes, participants in actual trading may experience technical failures such as system errors, connection issues, or trade execution delays, which can result in losses.

Personal Responsibility: Individuals are responsible for their own trading decisions. Any use of educational content or simulated trading provided by DayTraders.com should not be considered financial advice or an endorsement of specific trading strategies (simulated or actual). Participants should conduct thorough research and consult with professional financial advisors before engaging in actual trading.

The performance results displayed on DayTraders.com are based on hypothetical or simulated trading activities and do not represent actual trading results. Below are important points to consider regarding the limitations of hypothetical performance results.

Simulated Trading Environment: All trading conducted on DayTraders.com is within a simulated, educational environment. No real funds are used, and all performance outcomes are hypothetical in nature. These results may differ significantly from real-world trading outcomes where actual capital is at risk.

Limitations of Hypothetical Results: Hypothetical results are based on controlled conditions and do not reflect real market conditions, such as slippage, order execution delays, or liquidity issues. As such, these results may not accurately represent the challenges of actual trading.

No Guarantee of Future Performance: Hypothetical performance, whether positive or negative, should not be interpreted as an indication of future success in real-money trading. Actual trading results are influenced by many unpredictable factors, including market conditions and individual decision-making.

Psychological Factors: Simulated trading does not account for the psychological pressures experienced when trading with real funds. In actual trading, emotions such as fear and greed can affect decision-making, which is not reflected in the hypothetical results from DayTraders.com's simulated environment.

Educational and Demonstration Purposes Only: All hypothetical performance results displayed on DayTraders.com are for educational and demonstration purposes. They do not constitute an endorsement of any particular trading strategy or financial product. Participants should assess any trading strategy based on their own financial situation and risk tolerance before engaging in real-world trading.

By using DayTraders.com, you acknowledge that all trading activities are simulated and that hypothetical performance results may not reflect actual future trading performance.

Pass rates for the DayTraders.com evaluation program vary by program type, account size, market conditions, and individual trader experience. Not all participants who purchase an evaluation will pass. The evaluation is designed to be challenging and to assess a trader's ability to generate consistent simulated profits while adhering to defined risk management rules. Participants should not interpret any historical pass rate as a guarantee or prediction of their individual likelihood of success.

Our Evaluation and Pro Level Account programs are structured to simulate live market conditions as accurately as possible. This includes incorporating commissions, fees, and other relevant factors that traders would encounter in an actual trading environment. The primary purpose of the evaluation is to assess a trader's skill, discipline, and strategy in a realistic and controlled setting. It is important to emphasize that these programs are designed as comprehensive tests of trading competency, not as training platforms. Participants are expected to have a solid foundation in trading principles and risk management strategies before attempting the evaluation.

Passing the evaluation requires a high level of proficiency and is intentionally challenging, even for traders with significant experience. The evaluation is structured to measure a trader's ability to adhere to risk management rules, execute trades effectively, and maintain consistency over time. Due to its demanding nature, this program is not recommended for individuals with little or no trading experience. Novice traders may find the evaluation process particularly difficult and are encouraged to seek further education and practice before considering participation.

We recommend that individuals carefully evaluate their level of trading knowledge, experience, and preparedness prior to enrolling in the evaluation program. While the evaluation can serve as a valuable benchmark for experienced traders, it is not intended as a learning tool for beginners. By participating, traders acknowledge the inherent challenges and accept full responsibility for their trading decisions and performance outcomes.

Moderna–Merck Cancer Vaccine Shows Durable Benefit At 5 Years In High-Risk Melanoma

Ready to start trading futures?

LIMITED TIME ONLY

Get 90% Off Today!