AstraZeneca's Lung Cancer Combo Falls Short In Phase 3 Trial

On Monday, AstraZeneca Plc (NASDAQ:AZN) released topline data from the LATIFY Phase 3 trial of ceralasertib in combination with Imfinzi (durvalumab).

The trial did not meet the primary endpoint of overall survival (OS) versus standard-of-care docetaxel in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC).

The trial evaluated patients without actionable genomic alterations (AGAs) whose disease progressed on or after prior immunotherapy and platinum-based chemotherapy.

Also Read: AstraZeneca, GSK Among Executives Asked To Help Redesign UK Pricing Rules-Report

The combination of ceralasertib and Imfinzi was generally well tolerated, and the safety profile was consistent with the known profiles of each medicine, with no new safety concerns identified.

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Concurrently, AstraZeneca and Daiichi Sankyo Co., Ltd.’s (OTC:DSNKY) Enhertu (trastuzumab deruxtecan) has been ...

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AstraZeneca's Lung Cancer Combo Falls Short In Phase 3 Trial

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