Imbria Pharmaceuticals Raises $57.5M Series B Financing Round and Appoints Alvin Shih, MD as CEO

– Led by new investor Deep Track Capital, with participation from AN Ventures, Catalio Capital Management, Cytokinetics, Inc. and existing investors RA Capital Management and SV Health Investors,

– Proceeds to support advancement of ninerafaxstat for the treatment of non-obstructive hypertrophic cardiomyopathy (nHCM), with initiation of Phase 2b clinical trial planned in Q2 2025,

– Current Executive Chair, Alvin Shih, MD appointed as CEO; Rebecca Luse, Managing Director at Deep Track Capital, appointed to Board of Directors,

BOSTON, April 10, 2025 (GLOBE NEWSWIRE) -- Imbria Pharmaceuticals, Inc., a clinical stage biotechnology company developing novel therapies for cardiometabolic diseases with high unmet need, today announced the successful closing of a $57.5 million Series B financing with a top-tier syndicate of life science investors led by new investor, Deep Track Capital. Additional new investors participating in the financing include AN Ventures, Catalio Capital Management and Cytokinetics, Inc. Existing investors RA Capital Management and SV Health Investors also contributed to the financing.

Proceeds from the financing will be used to advance ninerafaxstat through a Phase 2b randomized, double-blind, placebo-controlled, clinical trial in non-obstructive hypertrophic cardiomyopathy (nHCM), called FORTITUDE-HCM. The company plans to initiate FORTITUDE-HCM in Q2 2025, with topline data in late 2026. Ninerafaxstat has previously shown positive results in multiple Phase 2a clinical trials in both nHCM (the IMPROVE-HCM trial) and heart failure with preserved ejection fraction (HFpEF) (the IMPROVE-DiCE trial). The results of IMPROVE-HCM were presented during a late-breaking clinical trial session at the American College of Cardiology Annual Scientific Session & Expo (ACC.24) and simultaneously published ...

https://www.benzinga.com/pressreleases/25/04/g44731945/imbria-pharmaceuticals-raises-57-5m-series-b-financing-round-and-appoints-alvin-shih-md-as-ceo